| Date | Time | Location | Home | Away | Score |
| Sat 04/24/10 | 08:30 AM | Major | Dodgers | Mets | |
| 08:30 AM | Minor | Red Sox | Blue Jays | ||
| 10:30 AM | Major | Tigers | Rangers | ||
| 10:30 AM | Minor | Pirates | White Sox | ||
| Sun 04/25/10 | 08:30 AM | Major | Rangers | Pirates | |
| 08:30 AM | Minor | Red Sox | Tigers | ||
| 10:30 AM | Major | Dodgers | White Sox | ||
| 10:30 AM | Minor | Mets | Blue Jays | ||
| Sun 05/02/10 | 08:30 AM | Major | Tigers | Rangers | |
| 08:30 AM | Minor | Pirates | Mets | ||
| 10:30 AM | Major | Dodgers | White Sox | ||
| 10:30 AM | Minor | Red Sox | Blue Jays | ||
| Sat 05/08/10 | 08:30 AM | Major | Mets | Rangers | |
| 08:30 AM | Minor | Pirates | Dodgers | ||
| 10:30 AM | Major | Tigers | Red Sox | ||
| 10:30 AM | Minor | Blue Jays | White Sox | ||
| Sat 05/15/10 | 08:30 AM | Major | Dodgers | Red Sox | |
| 08:30 AM | Minor | White Sox | Rangers | ||
| 10:30 AM | Major | Pirates | Blue Jays | ||
| 10:30 AM | Minor | Tigers | Mets | ||
| Sun 05/16/10 | 08:30 AM | Major | Tigers | Pirates | |
| 08:30 AM | Minor | Rangers | Red Sox | ||
| 10:30 AM | Major | Dodgers | Blue Jays | ||
| 10:30 AM | Minor | Mets | White Sox | ||
| Sat 05/22/10 | 08:30 AM | Major | White Sox | Tigers | |
| 08:30 AM | Minor | Blue Jays | Red Sox | ||
| 10:30 AM | Major | Rangers | Dodgers | ||
| 10:30 AM | Minor | Pirates | Mets | ||
| Sun 05/23/10 | 08:30 AM | Major | Red Sox | Mets | |
| 08:30 AM | Minor | Blue Jays | Dodgers | ||
| 10:30 AM | Major | Rangers | White Sox | ||
| 10:30 AM | Minor | Tigers | Pirates | ||
| Sat 05/29/10 | 08:30 AM | Major | Red Sox | Pirates | |
| 08:30 AM | Minor | White Sox | Tigers | ||
| 10:30 AM | Major | Rangers | Dodgers | ||
| 10:30 AM | Minor | Blue Jays | Mets | ||
| Sun 05/30/10 | 08:30 AM | Major | White Sox | Blue Jays | |
| 08:30 AM | Minor | Mets | Tigers | ||
| 10:30 AM | Major | Dodgers | Pirates | ||
| 10:30 AM | Minor | Red Sox | Rangers | ||
| Sat 06/05/10 | 08:30 AM | Major | Blue Jays | Rangers | |
| 08:30 AM | Minor | Tigers | Dodgers | ||
| 10:30 AM | Major | White Sox | Mets | ||
| 10:30 AM | Minor | Pirates | Red Sox | ||
| Sun 06/06/10 | 08:30 AM | Major | White Sox | Dodgers | |
| 08:30 AM | Minor | Blue Jays | Tigers | ||
| 10:30 AM | Major | Mets | Red Sox | ||
| 10:30 AM | Minor | Pirates | Rangers | ||
| Sat 06/12/10 | 08:30 AM | Major | Blue Jays | Mets | |
| 08:30 AM | Minor | White Sox | Pirates | ||
| 10:30 AM | Major | Rangers | Red Sox | ||
| 10:30 AM | Minor | Dodgers | Tigers | ||
| Sun 06/13/10 | 08:30 AM | Major | Red Sox | Dodgers | |
| 08:30 AM | Minor | Rangers | Mets | ||
| 10:30 AM | Major | Blue Jays | Pirates | ||
| 10:30 AM | Minor | Tigers | White Sox | ||
| Sat 06/19/10 | 08:30 AM | Major | Red Sox | White Sox | |
| 08:30 AM | Minor | Mets | Pirates | ||
| 10:30 AM | Major | Dodgers | Rangers | ||
| 10:30 AM | Minor | Tigers | Blue Jays | ||
| Sun 06/20/10 | 08:30 AM | Major | Pirates | Dodgers | |
| 08:30 AM | Minor | Blue Jays | White Sox | ||
| 10:30 AM | Major | Rangers | Tigers | ||
| 10:30 AM | Minor | Mets | Red Sox | ||
| Sat 06/26/10 | 08:30 AM | Major | Rangers | Blue Jays | |
| 08:30 AM | Minor | Mets | Dodgers | ||
| 10:30 AM | Major | Red Sox | Tigers | ||
| 10:30 AM | Minor | White Sox | Pirates | ||
| Sun 06/27/10 | 08:30 AM | Major | Pirates | Tigers | |
| 08:30 AM | Minor | Mets | Rangers | ||
| 10:30 AM | Major | Dodgers | Blue Jays | ||
| 10:30 AM | Minor | White Sox | Red Sox |